Jung SeungWoo, Jandrey Karl E
William R. Pritchard Veterinary Medical Teaching Hospital, University of California, Davis, CA 95616, USA.
J Vet Emerg Crit Care (San Antonio). 2012 Aug;22(4):483-7. doi: 10.1111/j.1476-4431.2012.00778.x. Epub 2012 Jul 5.
To demonstrate a critical role of artificial cardiac pacing to normalize severe bradyarrhythmia-induced hyperkalemia in a dog with third-degree atrioventricular (AV) block.
A dog was presented for evaluation of severe hyperkalemia and bradyarrhythmia. ECG revealed third-degree AV block with heart rate of 10-20 min, which was lower than usual ventricular escape rate. The etiology of severe hyperkalemia was considered secondary to significantly decreased renal perfusion and potassium excretion as a result of poor cardiac output caused by the AV block. Since potassium disorders may lead to life-threatening conditions such as cardiopulmonary arrest, artificial cardiac pacing was immediately pursued. Within 1 hour, serum potassium concentration was normalized, which confirmed that severe hyperkalemia occurred primarily due to third-degree AV block. The dog was then treated with permanent pacemaker implantation. A recheck evaluation 3-month post pacemaker implantation showed normal serum potassium concentration and the dog was clinically healthy.
This report describes hyperkalemia secondary to significantly decreased cardiac output and renal hypoperfusion caused by third-degree AV block. The authors propose that artificial cardiac pacing must be considered as an emergency treatment for bradyarrhythmia-induced hyperkalemia, which ultimately restores cardiac output and renal perfusion and normalizes serum potassium concentration.
证明人工心脏起搏在纠正一只患有三度房室(AV)阻滞的犬因严重缓慢性心律失常所致高钾血症中的关键作用。
一只犬因严重高钾血症和缓慢性心律失常前来评估。心电图显示三度AV阻滞,心率为10 - 20次/分钟,低于通常的心室逸搏率。严重高钾血症的病因被认为是继发于因AV阻滞导致的心输出量显著降低以及肾灌注和钾排泄减少。由于钾紊乱可能导致诸如心肺骤停等危及生命的情况,遂立即进行人工心脏起搏。1小时内血清钾浓度恢复正常,这证实严重高钾血症主要是由三度AV阻滞所致。随后该犬接受了永久性起搏器植入治疗。起搏器植入后3个月的复查评估显示血清钾浓度正常,且该犬临床健康。
本报告描述了由三度AV阻滞导致的心输出量显著降低和肾灌注不足继发的高钾血症。作者提出人工心脏起搏必须被视为缓慢性心律失常所致高钾血症的紧急治疗方法,其最终可恢复心输出量和肾灌注并使血清钾浓度正常化。