Mak Genevieve, Allen Justin
VCA California Animal Hospital Veterinary Specialty Group, Los Angeles, CA, 90025.
J Vet Emerg Crit Care (San Antonio). 2013 Nov-Dec;23(6):610-4. doi: 10.1111/vec.12101. Epub 2013 Sep 19.
To describe the occurrence of pheochromocytoma with third-degree atrioventricular (AV) block in 2 dogs.
Two dogs were referred for echocardiograms and further diagnostic and therapeutic treatment for third-degree AV block. Abdominal ultrasound of 1 dog revealed an adrenal mass, while that of the other dog revealed bilateral adrenal masses. While undergoing treatment, 1 dog experienced cardiac arrest and could not be revived with cardiopulmonary resuscitation, and the other dog was humanely euthanized. Histological findings of the masses were consistent with pheochromocytomas.
To the authors' knowledge, this is the first report with histologic evidence of pheochromocytoma and clinical presentation of third-degree AV block in dogs. In human literature, simultaneous presentation of both disease states is rare and has been infrequently reported.
描述2只犬发生嗜铬细胞瘤合并三度房室传导阻滞的情况。
2只犬因超声心动图检查及三度房室传导阻滞的进一步诊断和治疗而转诊。1只犬的腹部超声显示肾上腺肿块,另1只犬的腹部超声显示双侧肾上腺肿块。在治疗过程中,1只犬发生心脏骤停,心肺复苏未能使其复苏,另1只犬被实施安乐死。肿块的组织学检查结果与嗜铬细胞瘤一致。
据作者所知,这是首例有组织学证据支持的犬嗜铬细胞瘤及三度房室传导阻滞临床表现的报告。在人类文献中,这两种疾病状态同时出现的情况罕见,且鲜有报道。