Thompson Robin N, McNicholl Brian P
Emergency Department, Royal Victoria Hospital, Belfast, UK.
BMJ Case Rep. 2010 Aug 26;2010:bcr1120092444. doi: 10.1136/bcr.11.2009.2444.
This report describes a case of accidental needlestick injury involving a live equine vaccination, Equilis StrepE. A vet presented herself to the Emergency Department having accidentally injected herself with an equine vaccination. Her left thumb (injury site) was inflamed and had lymphangitis progressing proximally along her left arm. Her inflammatory markers were not raised. The swelling, erythma and lymphangitis had improved markedly with intravenous antibiotics. She had no sequelae at follow-up. Equilis StrepE is a vaccine for submucosal administration containing a modified live avirulent strain of Streptococcus equi subspecies equi (Strain TW). Group C streptococci infections are pathogenic in horses and uncommon in humans. A search of the literature revealed no prior case report of similar adverse reaction to this vaccine. The vaccine may have harmful effect on human health, if injected accidentally but more evidence needs to be collected.
本报告描述了一例涉及活马疫苗Equilis StrepE的意外针刺伤病例。一名兽医因意外给自己注射了马用疫苗而前往急诊科就诊。她的左手拇指(受伤部位)出现炎症,并且淋巴管炎沿左臂向近端发展。她的炎症指标未升高。静脉注射抗生素后,肿胀、红斑和淋巴管炎明显改善。随访时她没有后遗症。Equilis StrepE是一种用于粘膜下给药的疫苗,含有马链球菌马亚种的改良活无毒菌株(菌株TW)。C组链球菌感染在马中具有致病性,在人类中并不常见。文献检索未发现此前有关于该疫苗类似不良反应的病例报告。如果意外注射,该疫苗可能对人类健康产生有害影响,但需要收集更多证据。