Pande S, Joshi R, Pande R
Department of Rehabilitation Medicine, Changi General Hospital, Singapore.
BMJ Case Rep. 2010 Aug 3;2010:bcr0920092234. doi: 10.1136/bcr.09.2009.2234.
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm which can cause thrombohaemorrhagic complications usually involving microvasculature. Medium-sized arterial thrombosis has been reported, but coronary occlusion usually occurs with additional risk factors, for example, smoking, hyperlipidaemia and so on. We present a case of acute myocardial infarction (AMI) in a young man (29 years) with ET but without any coronary artery associated risk factors. He was successfully treated for his AMI and ET with cytoreductive treatment and has recovered well. Due to automated platelet counting, ET is being increasingly identified; early detection can prevent long-term complications, and patients can have normal life span.
原发性血小板增多症（ET）是一种慢性骨髓增殖性肿瘤，可导致血栓出血并发症，通常累及微血管。有报道称发生了中等大小动脉血栓形成，但冠状动脉闭塞通常在存在其他危险因素（如吸烟、高脂血症等）时发生。我们报告一例29岁患有ET但无任何冠状动脉相关危险因素的青年男性急性心肌梗死（AMI）病例。他通过细胞减灭治疗成功治疗了AMI和ET，恢复良好。由于自动血小板计数，ET越来越多地被识别出来；早期检测可预防长期并发症，患者可拥有正常寿命。
