Teo Mario K, Mathieson Calan, Carruthers Ross, Stewart Willie, Alakandy Likhith
Department of Neurosurgery, Institute of Neurological Sciences, Glasgow, UK.
Br J Neurosurg. 2012 Dec;26(6):868-71. doi: 10.3109/02688697.2012.697225. Epub 2012 Jul 6.
The spinal cord is an extremely rare site for primary central nervous system (CNS) lymphoma (< 1%). Very few cases of primary cauda equina (including conus) lymphoma were previously reported. We report such a case, and with literature review, discuss their clinical features, operative and histopathological findings. Although rare, with an increasing incidence of CNS lymphoma, they should be considered in the differential diagnosis of intradural lesions. Furthermore, with intraoperative smear to establish diagnosis, extensive surgery can be avoided. The controversial role of glucocorticoids in the management of these patients is also discussed.
脊髓是原发性中枢神经系统(CNS)淋巴瘤极为罕见的发病部位(<1%)。此前仅有极少例原发性马尾神经(包括圆锥)淋巴瘤的报道。我们报告了这样一例病例,并结合文献复习,讨论其临床特征、手术及组织病理学发现。尽管罕见,但随着CNS淋巴瘤发病率的上升,在硬膜内病变的鉴别诊断中应考虑到该病。此外,通过术中涂片确诊,可避免进行广泛的手术。本文还讨论了糖皮质激素在这些患者治疗中存在争议的作用。