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使用99mTc标记的焦磷酸盐进行闪烁心肌显像在诊断各种病因的心肌病中的敏感性。

The sensitivity of scintigraphic myocardial imaging by the use of 99mTc-labelled pyrophosphate in the diagnosis of cardiomyopathy of various etiology.

作者信息

Duska F, Vizda J, Kubícek J, Kafka P, Nesvadba Z, Zdánský P, Bastecký J

出版信息

Eur J Nucl Med. 1979 Apr 1;4(2):87-90. doi: 10.1007/BF00626076.

DOI:10.1007/BF00626076
PMID:227692
Abstract

A total of 10 patients were examined. In five children who suffered from secondary cardiomyopathy accompanying progressive muscular dystrophy scintigraphic examination of the myocardium was made using 99mTc-labelled pyrophosphate. In two cases the scan was distinctly positive, in three cases negative. Five men with poorly defined primary nonobstructive cardiomyopathy were examined too. The scan was positive in three cases and negative in two cases. The positivity of the pyrophosphate scan of the heart is therefore not pathonomonic of ischaemic damage. An increased accumulation of pyrophosphate in the myocardium in cardiomyopathy indicates an acute phase of the disease.

摘要

共对10名患者进行了检查。在5名患有继发性心肌病并伴有进行性肌营养不良的儿童中,使用99mTc标记的焦磷酸盐对心肌进行了闪烁扫描检查。2例扫描结果明显呈阳性,3例呈阴性。还对5名原发性非梗阻性心肌病诊断不明确的男性进行了检查。扫描结果3例呈阳性,2例呈阴性。因此,心脏焦磷酸盐扫描呈阳性并非缺血性损伤的特征性表现。心肌病患者心肌中焦磷酸盐的蓄积增加表明疾病处于急性期。

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1
The sensitivity of scintigraphic myocardial imaging by the use of 99mTc-labelled pyrophosphate in the diagnosis of cardiomyopathy of various etiology.使用99mTc标记的焦磷酸盐进行闪烁心肌显像在诊断各种病因的心肌病中的敏感性。
Eur J Nucl Med. 1979 Apr 1;4(2):87-90. doi: 10.1007/BF00626076.
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引用本文的文献

1
Pyrophosphate heart scan in patients with progressive systemic sclerosis.进行性系统性硬化症患者的焦磷酸盐心脏扫描
Br Heart J. 1982 Jan;47(1):90-3. doi: 10.1136/hrt.47.1.90.

本文引用的文献

1
Cardiac involvement in progressive muscular dystrophy.进行性肌营养不良症中的心脏受累情况。
Am Heart J. 1952 Feb;43(2):170-87. doi: 10.1016/0002-8703(52)90209-3.
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Progressive muscular dystrophy of the heart.进行性心肌营养不良
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Detection of acute myocardial infarction by technetium-99m polyphosphate.用锝-99m多聚磷酸盐检测急性心肌梗死
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Limited clinical diagnostic specificity of technetium-99m stannous pyrophosphate myocardial imaging in acute myocardial infarction.锝-99m焦磷酸亚锡心肌显像在急性心肌梗死中的临床诊断特异性有限。
Am J Cardiol. 1977 Jan;39(1):50-4. doi: 10.1016/s0002-9149(77)80010-6.
8
The specificity of the diffuse pattern of cardiac uptake in myocardial infarction imaging with technetium-99m stannous pyrophosphate.锝-99m焦磷酸亚锡用于心肌梗死显像时心脏摄取弥漫模式的特异性。
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Myocardial infarct imaging with technetium-99m phosphates.
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[Acute infarction of the myocardium in man. scintigraphic diagnosis using pyrophosphate designated 99m tc (author's transl)].[人体心肌急性梗死。使用99m锝标记的焦磷酸盐进行闪烁扫描诊断(作者译)]
Cas Lek Cesk. 1976 Sep 3;115(35):1076-9.