Murray M J
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Leesburg 22075.
J Am Vet Med Assoc. 1990 Dec 15;197(12):1635-8.
Hypothyroidism was diagnosed in a neonatal Thoroughbred foal that was weak, hypothermic, and septicemic. Administration of thyroid-releasing hormone elicited attenuated increases in concentrations of free and total triiodothyronine and thyroxine, as compared with a clinically normal, age-matched foal. The foal died of apparent respiratory insufficiency, pre- and postmortem findings compatible with hypothyroidism included hypothermia, large thyroid glands with distended, colloid-filled follicles, and severe, diffuse atelectasis, with thickened alveolar septae and degenerating alveolar squamous epithelial cells.
一匹新生纯种马驹被诊断为甲状腺功能减退，表现为虚弱、体温过低和败血症。与临床正常、年龄匹配的马驹相比，给予促甲状腺激素释放激素后，游离和总三碘甲状腺原氨酸及甲状腺素浓度的升高减弱。这匹马驹死于明显的呼吸功能不全，生前和死后与甲状腺功能减退相符的表现包括体温过低、甲状腺肿大且滤泡扩张并充满胶体，以及严重的弥漫性肺不张，伴有肺泡间隔增厚和肺泡鳞状上皮细胞变性。
