曲霉菌角膜炎在角膜环段植入术后。
Aspergillus fumigatus keratitis following intracorneal ring segment implantation.
机构信息
Department of ophthalmology, Faculty of medicine, Jordan University of Science & Technology, Irbid, Jordan.
出版信息
BMC Ophthalmol. 2012 Jul 6;12:19. doi: 10.1186/1471-2415-12-19.
BACKGROUND
Fungal keratitis has been rarely reported following intracorneal ring segment (ICRS) inmplantation. This paper aims to report a case of fungal keratitis with aspergillus fumigatus following ICRS implantation for correction of keratoconus.
METHODS
A retrospective chart review was done. Data including demographics, clinical history and presentation, microbiological analysis as well as clinical management were recorded.
RESULTS
A 34 year old male presented with pain, photophobia, redness and decreased vision in his right eye ten days after ICRS implantation for correction of keratoconus. Slit-lamp examination showed chemosis, ciliary injection, corneal abcess with ill defined edges and hypopyon. Microbiological analysis and culture of the corneal scrapes were positive for aspergillus fumigatus. The patient did not respond to medical treatment and ended up with corneal transplantation.
CONCLUSION
Although rare, fungal keratitis is a serious vision threatening complication that can complicate intrastromal ring implantation. Prompt and aggressive treatment is essential to prevent irreversible reduction of vision.
背景
在角膜内环段（ICRS）植入术后，真菌性角膜炎的报道很少见。本文旨在报告一例因圆锥角膜矫正而植入 ICRS 后感染烟曲霉菌的真菌性角膜炎病例。
方法
对病历进行回顾性分析。记录的数据包括人口统计学、临床病史和表现、微生物分析以及临床治疗情况。
结果
一名 34 岁男性因圆锥角膜矫正而植入 ICRS 后 10 天出现右眼疼痛、畏光、眼红和视力下降。裂隙灯检查显示球结膜水肿、睫状充血、角膜脓肿，边界不清，前房积脓。角膜刮片的微生物分析和培养均为烟曲霉菌阳性。患者对药物治疗无反应，最终进行了角膜移植。
结论
虽然罕见，但真菌性角膜炎是一种严重威胁视力的并发症，可能会使基质内环植入复杂化。及时积极的治疗对于防止视力不可逆转的下降至关重要。
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