Brook I
Naval Medical Research Institute, Bethesda, Maryland 20814-5145.
J Appl Bacteriol. 1990 Nov;69(5):697-700. doi: 10.1111/j.1365-2672.1990.tb01565.x.
The rate of bacterial growth of four Bacteroides fragilis group organisms was determined in agar and broth media. Exponential bacterial growth occurred in agar media within 4 to 8 h, while such growth was delayed in broth media and occurred within 12-24 h after inoculation. This phenomenon may explain why antimicrobials which manifest an 'inoculum effect' may show increased resistance to antimicrobials when tested in agar media.
测定了四种脆弱拟杆菌属微生物在琼脂和肉汤培养基中的细菌生长速率。在琼脂培养基中,细菌在4至8小时内呈指数生长,而在肉汤培养基中这种生长延迟,接种后12 - 24小时内才出现。这种现象可能解释了为何表现出“接种量效应”的抗菌药物在琼脂培养基中测试时可能显示出对抗菌药物的耐药性增加。