Belisle J, Maier S K, Tucker J A
3M Company, 3M Center, Corporate Research-Analytical, St. Paul, Minnesota 55144.
J Biomed Mater Res. 1990 Dec;24(12):1585-98. doi: 10.1002/jbm.820241204.
Biomer, a segmented polyether polyurethane, has been analyzed via hydrolysis/gas chromatography to determine its composition. In addition to the previously reported 4,4'-methylene bis(phenyl isocyanate) (MDI), polytetramethylene glycol (PTMO), and ethylenediamine, we now report the presence of diethylamine, 1,3-diaminocyclohexane and poly(diisopropylaminoethyl methacrylate-co-decyl methacrylate), Biomer's cloudy insoluble phase. In addition, a method is presented to characterize the methacrylate additive by molecular weight based on GPC. Also found by chromatography were the antioxidants Santowhite Powder and BHT. XPS shows no Si (silicone) on the Biomer surface, and a total chloride analysis reports no chloride (less than 0.03%). Time-of-flight SIMS data suggest evidence for the methacrylate additive at the surface, and mass spectroscopy can be interpreted as evidence for a diaminocyclohexane.
Biomer，一种嵌段聚醚聚氨酯，已通过水解/气相色谱法进行分析以确定其组成。除了先前报道的4,4'-亚甲基双（苯基异氰酸酯）（MDI）、聚四亚甲基二醇（PTMO）和乙二胺外，我们现在报告二乙胺、1,3-二氨基环己烷和聚（甲基丙烯酸二异丙基氨基乙酯-co-甲基丙烯酸癸酯）（Biomer的浑浊不溶相）的存在。此外，还提出了一种基于凝胶渗透色谱法按分子量表征甲基丙烯酸酯添加剂的方法。色谱分析还发现了抗氧化剂Santowhite Powder和丁基羟基甲苯（BHT）。X射线光电子能谱显示Biomer表面没有硅（硅氧烷），总氯分析报告没有氯（小于0.03%）。飞行时间二次离子质谱数据表明表面存在甲基丙烯酸酯添加剂，质谱可解释为存在二氨基环己烷的证据。
