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童年创伤对住院抑郁症患者药物治疗反应的影响。

The effect of childhood trauma on pharmacological treatment response in depressed inpatients.

机构信息

Department of Psychological Medicine, University of Otago, P.O. Box 4345, Christchurch 8140, New Zealand.

出版信息

Psychiatry Res. 2012 Dec 30;200(2-3):1058-61. doi: 10.1016/j.psychres.2012.06.015. Epub 2012 Jul 6.

DOI:10.1016/j.psychres.2012.06.015
PMID:22770764
Abstract

Childhood trauma and its association with pharmacological treatment response were examined in depressed inpatients. Treatment non-responders (n=31) reported significantly more severe trauma than treatment responders (n=25) and healthy controls (n=49), suggesting that the experience of childhood trauma in those hospitalised with depression can be detrimental to treatment success.

摘要

研究了抑郁症住院患者的童年创伤及其与药物治疗反应的关系。治疗无反应者(n=31)报告的创伤比治疗有反应者(n=25)和健康对照组(n=49)更严重,这表明在因抑郁症住院的患者中,童年创伤经历可能会对治疗效果产生不利影响。

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