Department of Psychological Medicine, University of Otago, P.O. Box 4345, Christchurch 8140, New Zealand.
Psychiatry Res. 2012 Dec 30;200(2-3):1058-61. doi: 10.1016/j.psychres.2012.06.015. Epub 2012 Jul 6.
Childhood trauma and its association with pharmacological treatment response were examined in depressed inpatients. Treatment non-responders (n=31) reported significantly more severe trauma than treatment responders (n=25) and healthy controls (n=49), suggesting that the experience of childhood trauma in those hospitalised with depression can be detrimental to treatment success.
研究了抑郁症住院患者的童年创伤及其与药物治疗反应的关系。治疗无反应者(n=31)报告的创伤比治疗有反应者(n=25)和健康对照组(n=49)更严重,这表明在因抑郁症住院的患者中,童年创伤经历可能会对治疗效果产生不利影响。