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应用RAND/UCLA方法分析急性胆囊炎最合适的手术治疗方法

[Analysis of the most appropriate surgical treatment for acute cholecystitis by applying the RAND/UCLA method].

作者信息

Díaz-Gómez Daniel, Parra-Membrives Pablo, Villegas-Portero Román, Molina-Linde Máximo, Gómez-Bujedo Lourdes, Lacalle-Remigio Juan Ramón

机构信息

Unidad de Cirugía Hepato-Bilio-Pancreática, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario de Valme, Sevilla, España.

出版信息

Cir Esp. 2012 Aug-Sep;90(7):453-9. doi: 10.1016/j.ciresp.2012.04.005. Epub 2012 Jul 6.

Abstract

INTRODUCTION

Acute cholecystitis (AC) is a common indication for cholecystectomy. Local circumstances and certain patient characteristics lead to high failure rates and complications in laparoscopic cholecystectomy (LC), and despite the experience gained, we still do not have a detailed list of indications which could minimise them.

MATERIAL AND METHOD

We used the RAND/UCLA Appropriateness Method (RAM) to evaluate 2 options, LC and open cholecystectomy (OC). An expert panel analysed its suitability after a literature review, a consensus meeting, and 2 rounds of scores on different clinical situations. The score of each scenario was analysed to establish the appropriateness level of each option.

RESULTS

At the end of the meeting there were 64 defined scenarios, with an agreement being reached on the indications in 67.18% of them. In 86.04% of the scenarios, the agreement was due to the appropriateness of the indications. When cholecystectomy was indicated, it was always by laparoscopy, while it was only occasionally by laparotomy. In patients with less than 72 h of onset, LC was always considered appropriate when there was sepsis, or even without this if the ultrasound data showed complicated AC.

CONCLUSIONS

There is still uncertainty as regards the management of AC, especially as regards the timing of the operation and the surgical approach, particularly in frail patients and with a clinical onset greater than 72 h. The RAND method can help to make decisions on the appropriateness of different therapeutic options.

摘要

引言

急性胆囊炎(AC)是胆囊切除术的常见指征。局部情况和某些患者特征导致腹腔镜胆囊切除术(LC)的失败率和并发症较高,尽管积累了经验,但我们仍没有一份能将这些情况降至最低的详细指征清单。

材料与方法

我们使用兰德/加州大学洛杉矶分校适宜性方法(RAM)来评估两种选择,即LC和开腹胆囊切除术(OC)。一个专家小组在文献综述、共识会议以及针对不同临床情况的两轮评分之后,分析了其适用性。对每个场景的评分进行分析,以确定每种选择的适宜性水平。

结果

会议结束时确定了64种场景,其中67.18%的场景在指征方面达成了一致。在86.04%的场景中,达成一致是因为指征的适宜性。当需要进行胆囊切除术时,通常采用腹腔镜手术,而开腹手术仅偶尔使用。在发病时间少于72小时的患者中,如果存在脓毒症,或者即使没有脓毒症但超声数据显示为复杂性AC,LC始终被认为是合适的。

结论

在AC的治疗管理方面仍存在不确定性,尤其是在手术时机和手术方式方面,特别是在体弱患者以及临床发病超过72小时的患者中。兰德方法有助于对不同治疗选择的适宜性做出决策。

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