减重手术能否降低阿尔茨海默病风险？
Can bariatric surgery reduce risk of Alzheimer's disease?
机构信息
Department of Psychology, University of Alabama, Tuscaloosa, AL, 35487, USA.
出版信息
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Dec 2;47:135-9. doi: 10.1016/j.pnpbp.2012.06.021. Epub 2012 Jul 4.
Abstract
Recent studies demonstrate that obesity is independently associated with poor neurocognitive outcomes, including cognitive impairment, increased risk for dementia, and regional alterations in brain structure. Bariatric surgery is an effective treatment for obesity and initial findings suggest that it may result in cognitive improvements. The current paper reviews and integrates recent research in this area, with a focus on potential mediators and moderators of neuropsychological outcome in bariatric surgery patients, including anesthetic and nutritional complications, and proposes novel avenues for continued study in this area.
摘要
最近的研究表明，肥胖与不良的神经认知结果独立相关，包括认知障碍、痴呆风险增加和大脑结构的区域改变。减重手术是肥胖的有效治疗方法，初步研究结果表明，它可能导致认知改善。本文综述了这一领域的最新研究，并重点探讨了减重手术患者神经心理学结果的潜在中介和调节因素，包括麻醉和营养并发症，并为该领域的进一步研究提出了新的途径。
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Improved memory function 12 weeks after bariatric surgery.减肥手术后 12 周记忆力改善。
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