Walø-Syversen Gro, Kvalem Ingela L, Kristinsson Jon, Eribe Inger L, Rø Øyvind, Brunborg Cathrine, Dahlgren Camilla Lindvall
Regional Department for Eating Disorders, Oslo University Hospital, Oslo, Norway.
Department of Psychology, University of Oslo, Oslo, Norway.
Front Psychol. 2021 Jan 8;11:607834. doi: 10.3389/fpsyg.2020.607834. eCollection 2020.
Severe obesity has been associated with reduced performance on tests of verbal memory in bariatric surgery candidates. There is also some evidence that bariatric surgery leads to improved verbal memory, yet these findings need further elucidation. Little is known regarding postoperative memory changes in the visual domain and how patients subjectively experience their everyday memory after surgery. The aim of the current study was to repeat and extend prior findings on postoperative memory by investigating visual, verbal, and self-reported everyday memory following surgery, and to examine whether weight loss and somatic comorbidity predict memory performance. The study was a prospective, observational study in which participants ( = 48) underwent cognitive testing at baseline, 1 and 2 years after bariatric surgery. Repeated measures analyses of variance revealed significantly poorer visual and verbal memory performance at the 1-year follow-up, with performance subsequently returning to baseline levels after 2 years. Verbal learning and self-reported everyday memory did not show significant postoperative changes. Memory performance at 1 year was not significantly predicted by weight loss, changes in C-reactive protein levels or postoperative somatic comorbidity (Type 2 diabetes, sleep apnea, and hypertension). The study demonstrated poorer visual and verbal memory performance at 1-year follow-up that returned to baseline levels after 2 years. These findings are in contrast to most previous studies and require further replication, however, the results indicate that postoperative memory improvements following bariatric surgery are not universal. Findings suggest that treatment providers should also be aware of patients potentially having poorer memory at 1 year following surgery.
重度肥胖与减肥手术候选者的言语记忆测试表现下降有关。也有一些证据表明减肥手术能改善言语记忆，但这些发现需要进一步阐明。关于术后视觉领域的记忆变化以及患者术后如何主观体验日常记忆，目前知之甚少。本研究的目的是通过调查手术后的视觉、言语和自我报告的日常记忆来重复和扩展先前关于术后记忆的研究结果，并检验体重减轻和躯体合并症是否能预测记忆表现。该研究是一项前瞻性观察性研究，参与者（n = 48）在减肥手术前、术后1年和2年接受认知测试。重复测量方差分析显示，在1年随访时视觉和言语记忆表现显著较差，2年后表现随后恢复到基线水平。言语学习和自我报告的日常记忆术后未显示出显著变化。1年时的记忆表现不能由体重减轻、C反应蛋白水平变化或术后躯体合并症（2型糖尿病、睡眠呼吸暂停和高血压）显著预测。该研究表明，在1年随访时视觉和言语记忆表现较差，2年后恢复到基线水平。这些发现与大多数先前的研究相反，需要进一步重复验证，然而，结果表明减肥手术后记忆改善并非普遍现象。研究结果表明，治疗提供者也应意识到患者在术后1年可能记忆较差。
