Department of Radiology, William Beaumont Hospital, Royal Oak, MI 48073, USA.
Spine (Phila Pa 1976). 2012 Oct 1;37(21):E1361-3. doi: 10.1097/BRS.0b013e318266e4ab.
Case report.
To report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.
A 46-year-old man without previous diagnosis of alkaptonuria underwent evaluation for progressive back pain revealing a T1-hyperintense disc herniation at the L3-L4 level. Discectomy recovered a blackened disc that was pathologically confirmed to be nucleus pulposus with alkaptonuric involvement. The differential diagnosis of a T1-hyperintense, T2-hypointense disc on magnetic resonance imaging is discussed, with emphasis on the pathophysiology of alkaptonuria.
A single patient is reported.
Pathologically proven patient presentation with radiological and pathological images.
We report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.
病例报告。
报告一例罕见的尿黑酸尿症表现为 T1 高信号椎间盘突出症的病例。
一名 46 岁男性，无尿黑酸尿症既往诊断，因进行性腰痛接受评估，显示 L3-L4 水平 T1 高信号椎间盘突出症。椎间盘切除术恢复了一个变黑的椎间盘，病理证实为伴有尿黑酸尿症的髓核。讨论了磁共振成像上 T1 高信号、T2 低信号椎间盘的鉴别诊断，重点介绍了尿黑酸尿症的病理生理学。
报告了一例单一患者。
有影像学和病理图像证实的患者表现。
我们报告一例罕见的尿黑酸尿症表现为 T1 高信号椎间盘突出症。
