Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL, USA.
J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):241-6. doi: 10.1176/appi.neuropsych.11090207.
The relationship between psychotic disorders, in particular, schizophrenia, and neurodevelopmental abnormalities has been conceptualized in the latest literature. Dandy-Walker variant, defined by cystic dilatation of the fourth ventricle and hypoplasia of the inferior portion of the vermis without enlargement of the posterior fossa, is a distinctive entity believed to represent a mild subtype of Dandy-Walker complex. The authors hypothesize a correlation between new onset of psychosis and cerebellar abnormalities in an adolescent patient.
最新文献中提出,精神障碍,尤其是精神分裂症与神经发育异常之间存在关联。Dandy-Walker 变异型,其特征为第四脑室囊性扩张和蚓部下份发育不全,而后颅窝无扩大,被认为是 Dandy-Walker 复合体的轻度亚型。作者假设在一名青少年患者中,精神疾病的新发病例与小脑异常之间存在相关性。