Abdul Haleem, Burns Joseph, Estevez Andrea, Nasr El-Nimer Carlos, Ekinde Brinsley, Lacaille Sherard
Kendall Regional Medical Center, Miami, FL 33175, USA.
Florida International University, Herbert Wertheim College of Medicine, Miami, FL 33199, USA.
Case Rep Neurol Med. 2019 Sep 17;2019:1450703. doi: 10.1155/2019/1450703. eCollection 2019.
The Dandy-Walker Malformation was first described in 1914 by Dandy and Blackfan and is characterized by hypoplasia of the vermis, pseudocystic fourth ventricle, upward displacement of the tentorium, torcular and lateral sinuses, and anteroposterior enlargement of the posterior fossa. This syndrome commonly manifests as hydrocephalus in children, though rare adult cases have been reported. The literature reveals adult symptomatology including brainstem infarction, psychosis, and neuromuscular disease. Stroke is an exceptionally rare presentation of this malformation, with only one ischemic event reported in the literature. This case offers a rare opportunity for diagnosis in an adult presenting with a hemorrhagic stroke of the basal ganglia in an otherwise asymptomatic young adult male. To the best of our knowledge, this is the first reported case of a hemorrhagic stroke in an adult patient with Dandy-Walker Malformation.
丹迪-沃克畸形于1914年由丹迪和布莱克范首次描述，其特征为小脑蚓部发育不全、第四脑室假性囊肿、小脑幕、窦汇和外侧窦向上移位，以及后颅窝前后径增大。该综合征在儿童中通常表现为脑积水，不过也有罕见的成人病例报道。文献显示成人症状包括脑干梗死、精神病和神经肌肉疾病。中风是这种畸形极其罕见的表现，文献中仅报道过一例缺血性事件。该病例为一名无症状的年轻成年男性出现基底节出血性中风的成人诊断提供了难得的机会。据我们所知，这是首例报道的患有丹迪-沃克畸形的成年患者发生出血性中风的病例。
