Rosińska Justyna, Lukasik Maria, Kozubski Wojciech
Katedra i Klinika Neurologii, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu, ul. Przybyszewskiego 49, 60-355 Poznań.
Neurol Neurochir Pol. 2012 May-Jun;46(3):263-70. doi: 10.5114/ninp.2012.28916.
The primary hepatotropic viruses are associated with various extrahepatic manifestations including peripheral nervous system disorders. The pathogenesis of these complications is not clear-cut. Patients with confirmed liver damage coexisting with peripheral nervous system manifestations, especially Guillain-Barré syndrome, mononeuropathy, mononeuropathy multiplex and polyneuropathy should be screened for the viral hepatitis in the differential diagnosis. There are no defined strategies of treatment for these manifestations, so the therapy should be individualized. The purpose of this review is to discuss the etiology, pathogenesis and treatment of the neuropathies in the course of primary hepatotropic viral infections such as hepatitis A, B, C and E viruses.
主要嗜肝病毒与包括周围神经系统疾病在内的各种肝外表现有关。这些并发症的发病机制尚不清楚。在鉴别诊断中，对于确诊有肝损伤且伴有周围神经系统表现，尤其是吉兰-巴雷综合征、单神经病、多发性单神经病和多发性神经病的患者，应筛查病毒性肝炎。对于这些表现，目前尚无明确的治疗策略，因此治疗应个体化。本综述的目的是讨论甲型、乙型、丙型和戊型肝炎病毒等原发性嗜肝病毒感染过程中神经病变的病因、发病机制和治疗。
