实验性藏猴驯化及其在眼压测量中的应用。
Experimental Tibetan monkey domestication and its application for intraocular pressure measurement.
作者信息
Yi Yong, Zeng Tao, Zhou Liang, Cai Su-Ping, Yin Yan, Wang Yun, Cao Xu, Xu Yue-Zhong, Wang Hong-Xing, Liu Xu-Yang
机构信息
Institute of Laboratory Animals of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610212, Sichuan Province, China.
出版信息
Int J Ophthalmol. 2012;5(3):277-80. doi: 10.3980/j.issn.2222-3959.2012.03.05. Epub 2012 Jun 18.
AIM
To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque.
METHODS
The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training.
RESULTS
Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVet® rebound tonometer without sedation or anesthesia and their IOP values were similar to other primates.
CONCLUSION
Human-cultivated Thibetan monkeys are tamable, and can be used for biomedical research such as ophthalmic research without anesthesia.
目的
训练藏猕猴在清醒状态下测量眼压，并获取清醒藏猕猴的正常眼压。
方法
训练基于奖励条件行为。本训练采用食物刺激和人猴互动。
结果
经过训练的藏猕猴在未使用镇静或麻醉的情况下，能平静地接受TonoVet®回弹式眼压计测量眼压，其眼压值与其他灵长类动物相似。
结论
人工饲养的藏猕猴是可驯化的，可用于无需麻醉的生物医学研究，如眼科研究。
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