Department of Internal Medicine, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Eur Rev Med Pharmacol Sci. 2012 May;16(5):594-9.
Oxidative stress is believed to have a role in the development of chronic diseases. It is also known that long-term night and shift work in nurses might be associated with many health-related problems like fatigue, sleep problems, anxiety and difficulties in maintaining regular lifestyles.
In this study, we aimed to evaluate the changes of oxidative stress parameters and anxiety indexes of the nurses on day and night shifts.
One hundred and twenty nurses in ordinary service and intensive care unit (ICU) were enrolled to the study. Subjects were divided into 2 groups; group 1 (n = 60) consisted of nurses working in a day shift and group 2 (n = 60) as working in the night shift. Further, both groups were divided in to 2 groups again; group la and 2a (both n = 30) who working in the ICU, group 1b and 2b (both n = 30) in the ordinary service. Just before and the end of the shifts, blood samples were obtained to measure total antioxidant status (TAS) and total oxidant status (TOS). Oxidative stress index (OSI) was calculated. Anxiety index were determined at the end of the shift using State-Trait Anxiety Inventory index.
Oxidative stress parameters were increased in all nurses at the end of the day and night shifts (p < 0.05). However, both in service and ICU nurses TAS, TOS, and OSI levels were not significantly different at the beginning and the end of the shifts (p > 0.05). Anxiety indexes of each ordinary service and ICU nurses were found to be similar (p > 0.05).
Ordinary service and ICU nurses' oxidative stress parameters and anxiety indexes were not different and all nurses suffer the similar effects of the shifts both in day and night.
氧化应激被认为与慢性疾病的发展有关。众所周知，护士长期从事夜班和轮班工作可能会导致许多与健康相关的问题，如疲劳、睡眠问题、焦虑和难以保持规律的生活方式。
本研究旨在评估日夜班护士的氧化应激参数和焦虑指数的变化。
将 120 名普通病房和重症监护病房（ICU）的护士纳入研究。将受试者分为两组；第 1 组（n=60）由上白班的护士组成，第 2 组（n=60）由上夜班的护士组成。此外，两组再次分为两组；ICU 组 1a 和 2a（均 n=30），普通病房组 1b 和 2b（均 n=30）。在换班前和换班结束时，采集血样以测量总抗氧化状态（TAS）和总氧化状态（TOS）。计算氧化应激指数（OSI）。在换班结束时使用状态-特质焦虑量表指数确定焦虑指数。
所有护士在日夜班结束时氧化应激参数均升高（p<0.05）。然而，普通病房和 ICU 护士在换班前和换班结束时 TAS、TOS 和 OSI 水平均无显著差异（p>0.05）。普通病房和 ICU 护士的焦虑指数相似（p>0.05）。
普通病房和 ICU 护士的氧化应激参数和焦虑指数没有差异，所有护士在日夜班都受到类似的影响。
