[低反应者中第2天与第3天胚胎移植的妊娠结局]
[Pregnancy outcomes of day-2 versus day-3 embryo transfer in poor responders].
作者信息
Xin Zhi-Min, Zhang Quan-Le, Sun Ying-Pu, Jin Hai-Xia, Song Wen-Yan
机构信息
Center of Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
出版信息
Zhonghua Nan Ke Xue. 2012 Jun;18(6):522-6.
OBJECTIVE
To investigate whether the day of embryo transfer (day 2 or day 3) affects clinical pregnancy outcomes in poor responder patients.
METHODS
We retrospectively analyzed the pregnancy rates of 265 initial fresh cycles of in vitro fertilization-embryo transfer (IVF-ET), all transferred on day 2 (n = 169) or day 3 (n = 96) irrespective of quality because of an extremely low number of available embryos.
RESULTS
Among the poor responders aged < 35 years, a higher rate of clinical pregnancy was achieved in the day-3 than in the day-2 group (50% vs 32.43% ; RR = 0.65, 95% CI: 0.43 - 0.99), and among those aged years, the two groups showed similar pregnancy outcomes.
CONCLUSION
Shortening the time of embryo culture has no obvious benefit for the pregnancy outcome. For the poor responders under 35 years of age, day-3 embryo transfer may afford an even higher rate of clinical pregnancy.
目的
探讨胚胎移植日（第2天或第3天）是否会影响低反应患者的临床妊娠结局。
方法
我们回顾性分析了265个首次新鲜周期的体外受精-胚胎移植（IVF-ET）的妊娠率，由于可用胚胎数量极少，所有胚胎均在第2天（n = 169）或第3天（n = 96）进行移植，而不考虑胚胎质量。
结果
在年龄<35岁的低反应患者中，第3天移植组的临床妊娠率高于第2天移植组（50% 对32.43%；RR = 0.65，95%CI：0.43 - 0.99），而在年龄较大的患者中，两组的妊娠结局相似。
结论
缩短胚胎培养时间对妊娠结局无明显益处。对于35岁以下的低反应患者，第3天胚胎移植可能具有更高的临床妊娠率。
Zotero 插件