Institute on Multicultural Health, Henry Ford Health System, Detroit, MI, USA.
Am J Manag Care. 2012 Jun;18(6):303-11.
To describe lipid management over time in a cohort of insured patients with diabetes and evaluate differences between African American and white patients.
Automated claims data were used to identify a cohort of 11,411 patients with diabetes in 1997 to 1998. Patients were followed through 2007.
Rates of hypercholesterolemia testing, treatment, and goal attainment were measured annually. Treatment was determined by a claim for lipid-lowering agents, and goal attainment was defined as a low-density lipoprotein cholesterol (LDL-C) level <100 mg/dL.
During the study period, LDL-C testing increased from 48% to 70% among African American patients and from 61% to 77% among white patients. Treatment with lipid-lowering drugs increased from 23% to 56% among African American patients and 33% to 61% among white patients. The proportion at goal increased from 35% to 76% and from 24% to 59% among white and African American patients, respectively. African American patients were less likely to be tested for LDL-C (odds ratio [OR] 0.79; 95% confidence interval [CI] 0.73-0.86), treated with lipidlowering agents (OR 0.72; 95% CI 0.65-0.80), have their medication dosage altered (OR 0.65; 95% CI 0.59-0.73), or attain LDL-C goal (OR 0.59; 95% CI 0.56-0.63) compared with white patients.
Although rates of LDL-C testing, treatment, and goal attainment improved over time, racial disparities in dyslipidemia management continued to exist. Further studies to determine the causes of differences in management by race are warranted.
描述一个糖尿病参保患者队列随时间推移的血脂管理情况,并评估非裔美国患者和白种患者之间的差异。
使用自动理赔数据确定了 1997 年至 1998 年期间的 11411 例糖尿病患者队列。对患者进行了随访至 2007 年。
每年测量高胆固醇血症检测、治疗和达标率。通过降脂药物的索赔来确定治疗情况,将低密度脂蛋白胆固醇(LDL-C)水平<100mg/dL 定义为达标。
在研究期间,非裔美国患者的 LDL-C 检测率从 48%增加到 70%,白种患者从 61%增加到 77%。非裔美国患者使用降脂药物治疗的比例从 23%增加到 56%,白种患者从 33%增加到 61%。达标比例从 35%增加到 76%和 24%增加到 59%,分别在白种和非裔美国患者中。与白种患者相比,非裔美国患者接受 LDL-C 检测的可能性更低(比值比[OR]0.79;95%置信区间[CI]0.73-0.86)、接受降脂药物治疗的可能性更低(OR0.72;95%CI0.65-0.80)、改变药物剂量的可能性更低(OR0.65;95%CI0.59-0.73)或达到 LDL-C 目标的可能性更低(OR0.59;95%CI0.56-0.63)。
尽管 LDL-C 检测、治疗和达标率随时间推移而提高,但血脂异常管理方面的种族差异仍然存在。需要进一步研究确定种族管理差异的原因。