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腹腔镜全直肠系膜切除术:早期和晚期结果

Laparoscopic total mesorectal excision: early and late results.

作者信息

Cecconello I, Araujo S E A, Seid V E, Nahas S C

机构信息

Department of Gastroenterology, University of Sao Paulo Medical School, Sao Paulo, Brazil.

出版信息

Asian J Endosc Surg. 2011 Aug;4(3):99-106. doi: 10.1111/j.1758-5910.2011.00090.x. Epub 2011 Jun 20.

Abstract

BACKGROUND

Laparoscopic colectomy is superior to open colectomy in terms of short-term surgical outcomes. There is solid evidence indicating that laparoscopic and open surgery are equally effective for colon cancer, but for rectal cancer, the issues of neoadjuvant treatment, the need for total mesorectal excision and autonomic nerve preservation, and the technical demands of a well-constructed low colorectal or coloanal anastomosis challenge even the most specialized surgeons. This review discusses the available evidence on short-term and long-term outcomes after laparoscopic total mesorectal excision for rectal cancer.

DATA SOURCES

Systematic MEDLINE and Embase searches of outcomes on laparoscopic total mesorectal excision were conducted and data were retrieved.

CONCLUSIONS

Information on short-term and long-term outcomes after laparoscopic total mesorectal excision remains limited. Data are mainly retrospective and from randomized studies based on few cases that had minimal follow-up. Early non-oncologic surgical outcomes seem improved after laparoscopy, but an increased rate of positive circumferential resection margins has been detected. Though scarce, the available evidence on recurrence and survival does not indicates disadvantages to the laparoscopic approach.

摘要

背景

在短期手术结果方面,腹腔镜结肠切除术优于开放结肠切除术。有确凿证据表明,腹腔镜手术和开放手术对结肠癌同样有效,但对于直肠癌,新辅助治疗问题、全直肠系膜切除及自主神经保留的必要性,以及构建良好的低位结直肠或结肠肛管吻合术的技术要求,即便对最专业的外科医生来说也是挑战。本综述讨论了腹腔镜全直肠系膜切除治疗直肠癌后短期和长期结果的现有证据。

数据来源

对腹腔镜全直肠系膜切除的结果进行了系统的MEDLINE和Embase检索并获取数据。

结论

腹腔镜全直肠系膜切除术后短期和长期结果的信息仍然有限。数据主要是回顾性的,且来自基于少数病例且随访时间短的随机研究。腹腔镜手术后早期非肿瘤手术结果似乎有所改善,但已检测到环周切缘阳性率增加。关于复发和生存的现有证据虽然稀少,但并未表明腹腔镜手术方法存在劣势。

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