Mercado Jennifer Loh, Purvin Valerie A, Kawasaki Aki, WuDunn Darrell
Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46290, USA.
Arch Ophthalmol. 2012 Jul;130(7):863-7. doi: 10.1001/archophthalmol.2012.581.
To better define the concordance of visual loss in patients with nonarteritic anterior ischemic optic neuropathy (NAION).
The medical records of 86 patients with bilateral sequential NAION were reviewed retrospectively, and visual function was assessed using visual acuity, Goldmann visual fields, color vision, and relative afferent papillary defect. A quantitative total visual field score and score per quadrant were analyzed for each eye using the numerical Goldmann visual field scoring method.
Outcome measures were visual acuity, visual field, color vision, and relative afferent papillary defect. A statistically significant correlation was found between fellow eyes for multiple parameters, including logMAR visual acuity (P=.01), global visual field (P<.001), superior visual field (P<.001), and inferior visual field (P<.001). The mean deviation of total (P<.001) and pattern (P<.001) deviation analyses was significantly less between fellow eyes than between first and second eyes of different patients.
Visual function between fellow eyes showed a fair to moderate correlation that was statistically significant. The pattern of vision loss was also more similar in fellow eyes than between eyes of different patients. These results may help allow better prediction of visual outcome for the second eye in patients with NAION.
更好地明确非动脉炎性前部缺血性视神经病变（NAION）患者双眼视力丧失的一致性。
回顾性分析86例双侧先后发生NAION患者的病历，采用视力、Goldmann视野、色觉和相对传入性瞳孔障碍评估视功能。使用Goldmann视野数值评分法分析每只眼睛的定量全视野得分和每个象限的得分。
观察指标为视力、视野、色觉和相对传入性瞳孔障碍。在多参数方面，双眼之间存在显著的统计学相关性，包括logMAR视力（P = 0.01）、全视野（P < 0.001）、上半视野（P < 0.001）和下半视野（P < 0.001）。双眼之间总偏差（P < 0.001）和模式偏差（P < 0.001）分析的平均偏差明显小于不同患者的第一眼和第二眼之间的偏差。
双眼之间的视功能显示出中等程度的相关性，具有统计学意义。双眼之间视力丧失的模式也比不同患者的眼睛之间更为相似。这些结果可能有助于更好地预测NAION患者第二眼的视觉预后。
