Babić Z, Ugarković B, Ivancević D, Babić D
Department of Nuclear Medicine, University Hospital Center, Zagreb, Yugoslavia.
Nuklearmedizin. 1990 Nov;29(5):204-9.
A method is presented which combines gastro-oesophageal reflux quantification and oesophageal transit measurement so as to differentiate true reflux from residual oesophageal activity. A group of 33 subjects with gastro-oesophagitis reflux symptoms and endoscopically confirmed reflux oesophagitis and a group of 21 asymptomatic subjects with normal oesophageal, gastric and duodenal endoscopic findings were examined. The subjects were given 37 MBq 99mTc-Sn-colloid in saline orally and then scintiscanned dynamically. The gastro-oesophageal quantification was done after transit measurement and after the oesophageal time activity (to detect residual oesophageal activity) reached its minimum. The difference in the reflux indices between the two groups was highly significant. In low-grade oesophagitis measured reflux was lower than in higher grades of disease. Only 4.7% false-positive results were observed with a specificity of 95%, indicating that this method may be superior to methods published earlier.
本文介绍了一种结合胃食管反流定量和食管转运测量的方法，以区分真正的反流与食管残余活动。对一组33名有胃食管反流症状且经内镜证实为反流性食管炎的受试者和一组21名食管、胃和十二指肠内镜检查结果正常的无症状受试者进行了检查。受试者口服含37MBq 99mTc-Sn-胶体的生理盐水，然后进行动态闪烁扫描。在转运测量后以及食管时间活性（以检测食管残余活动）达到最小值后进行胃食管定量。两组之间的反流指数差异非常显著。在轻度食管炎中，测量到的反流低于疾病程度较高的情况。观察到假阳性结果仅为4.7%，特异性为95%，表明该方法可能优于早期发表的方法。
