Gratz K F, Meyer H J, Creutzig H, Pichlmayr R, Hundeshagen H
Nuklearmedizin. 1985 Feb;24(1):35-8.
Biliary and pancreatic juice has been implicated as a cause of regional inflammation or carcinoma after gastric surgery. We studied 38 patients after gastrectomy using a modification of cholescintigraphy (185 mBq 99m-Tc-DESIDA i.v.). As soon as the tracer had reached the duodenum, a dynamic study (30 min, 120 frames) was started. Thereafter a static image of the epigastrium and thorax in the anterior view with more than 1000 cts/cm2 was recorded. This procedure was repeated after a meal. Of 29 patients without complaints only 4 had a reflux into the jejunal loop. By contrast in 7 of 9 patients with suggestive symptoms this examination demonstrated bile reflux which reached the oesophagus in 6 cases. A stenosis of the distal oesophagus prevented oesophageal reflux in one patient. 2 patients with oesophageal reflux had a history of oesophageal stenosis and oesophagitis confirmed by endoscopy. The remaining 2 patients without demonstrable reflux had neither oesophagitis nor radiologically verified reflux. Cholescintigraphy as modified by us may detect clinical relevant bile reflux into the oesophagus. This is important for surgeons selecting patients with potential benefit from a reoperation. Since most patients with complaints after gastrectomy have had demonstrable bile reflux, reflux-reducing surgical techniques should be used in all.
胆汁和胰液被认为是胃手术后局部炎症或癌变的一个原因。我们采用一种改良的胆系闪烁显像法(静脉注射185 MBq 99m锝-二乙基乙酰苯胺)对38例胃切除术后患者进行了研究。一旦示踪剂到达十二指肠,即开始动态研究(30分钟,120帧)。此后,记录上腹部和胸部前位静态图像,计数超过1000 cts/cm²。进食后重复此操作。在29例无不适主诉的患者中,只有4例出现胆汁反流至空肠袢。相比之下,在9例有提示性症状的患者中,7例经此项检查显示有胆汁反流,其中6例胆汁反流至食管。1例患者因食管远端狭窄阻止了食管反流。2例有食管反流的患者有食管狭窄病史,且经内镜检查证实有食管炎。其余2例未显示反流的患者既无食管炎,影像学检查也未证实有反流。我们改良的胆系闪烁显像法可能检测出临床上有意义的胆汁反流至食管的情况。这对于外科医生选择可能从再次手术中获益的患者很重要。由于大多数胃切除术后有不适主诉的患者都有可证实的胆汁反流,因此所有患者都应采用减少反流的手术技术。