手性磷酸催化不对称合成 CF3-或-CF2-取代的四氢喹啉。
The asymmetric synthesis of CF3- or -CF2-substituted tetrahydroquinolines by employing a chiral phosphoric acid as catalyst.
机构信息
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, P. R. China.
出版信息
Chem Commun (Camb). 2012 Aug 11;48(62):7738-40. doi: 10.1039/c2cc18064b.
PMID:22779079
Abstract
CF(3)- or -CF(2)-containing tetrahydroquinolines have been asymmetrically synthesized from the reaction of fluorinated N-arylimines with benzyl N-vinylcarbamate in the presence of a chiral phosphoric acid.
摘要
含 CF(3)-或 CF(2)-的四氢喹啉已通过手性磷酸存在下氟化 N-芳基亚胺与苄基 N-乙烯基氨基甲酸酯的反应不对称合成。
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