Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, P. R. China.
Chem Commun (Camb). 2012 Aug 11;48(62):7738-40. doi: 10.1039/c2cc18064b.
CF(3)- or -CF(2)-containing tetrahydroquinolines have been asymmetrically synthesized from the reaction of fluorinated N-arylimines with benzyl N-vinylcarbamate in the presence of a chiral phosphoric acid.
含 CF(3)-或 CF(2)-的四氢喹啉已通过手性磷酸存在下氟化 N-芳基亚胺与苄基 N-乙烯基氨基甲酸酯的反应不对称合成。
