Niemczyk Stanisław, Piotrowska Małgorzata, Szamotulska Katarzyna
Wojskowy Instytut Medyczny w Warszawie, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii, CSK MON.
Pol Merkur Lekarski. 2012 May;32(191):313-7.
The authors present literature review of usefulness of serum creatinine concentration measurements in comparison with cystatin C concentration for assessment renal function in chronic kidney disease and concomitant diseases. In this article different methods of determining renal filtration are critically discussed. In comparison with creatinine, cystatin C is a good parameter for assessing stable renal function and their early damage. It is a marker of subclinical disorders in chronic renal failure which is also useful in assessing renal dysfunction in coexisting diseases. Cystatin C is more precise than creatinine especially in pediatric, elderly, diabetic and oncological patients. It is more accurate because it is not associated with amount of muscle mass and nutritional status. Among many parameters cystatin C is a promising marker broadening diagnostic tools in nephrology.
作者对血清肌酐浓度测量与胱抑素C浓度相比在评估慢性肾病及相关疾病肾功能方面的有用性进行了文献综述。本文对不同的肾滤过测定方法进行了批判性讨论。与肌酐相比，胱抑素C是评估稳定肾功能及其早期损伤的良好参数。它是慢性肾衰竭亚临床疾病的标志物，在评估并存疾病中的肾功能障碍方面也很有用。胱抑素C比肌酐更精确，尤其是在儿科、老年、糖尿病和肿瘤患者中。它更准确，因为它与肌肉量和营养状况无关。在众多参数中，胱抑素C是一种有前景的标志物，可拓宽肾脏病学的诊断工具。
