津巴布韦黑人中人类白细胞抗原（HLA）与类风湿性关节炎之间的关联。
The association between HLA and rheumatoid arthritis in Zimbabwean blacks.
作者信息
Martell R W, Stein M, Davis P, West G, Emmanuel J, du Toit E D
机构信息
Provincial Laboratory for Tissue Immunology, Cape Town, South Africa.
出版信息
Tissue Antigens. 1990 Sep;36(3):125-6. doi: 10.1111/j.1399-0039.1990.tb01813.x.
Abstract
HLA-A, B, C, DR and DQ typing was done on 26 black Zimbabweans with rheumatoid arthritis and the respective antigen frequencies were compared with those in a group of 119 normal individuals from the same ethnic background. Only the DR4 antigen was significantly increased in frequency in the patients, confirming the association with this disease seen in other Black African populations.
摘要
对26名患类风湿性关节炎的津巴布韦黑人进行了HLA - A、B、C、DR和DQ分型，并将各自的抗原频率与119名来自相同种族背景的正常个体组成的群体进行了比较。仅患者中DR4抗原的频率显著增加，证实了在其他非洲黑人人群中所见到的与该疾病的关联。
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