Chen Xin, Zeng Mei-ying, Li Yong, Xu Jing, Lin Jiang-tao
Department of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2012 Mar;35(3):167-70.
To investigate the correlation between exercise-induced bronchoconstriction and atopy.
Exercise-induced bronchoconstriction (EIB) was defined by free running asthma screening test. Atopy was defined by serum total IgE level and skin allergen test. Airway hyperreactivity was determined by bronchial provocation test. For a matched pair study, all EIB and some non-EIB students received serum total IgE measurements, skin allergen test and bronchial provocation test. All data were calculated by correlation analysis to investigate the correlation between EIB and atopy.
Totally 773 students participated in the free running screening test, and 89 students (11.5%) were diagnosed as having EIB. The serum total IgE level exceeded the normal range in 16 among the 89 EIB students, but in 10 among the 70 non-EIB students. Statistical analysis (χ(2) test) did not support the correlation between atopy and EIB. Fifty EIB students received bronchial provocation test, but only 1 showed airway hyperreactivity.
There was no correlation between atopy and EIB, and airway hyperreactivity was absent in most of the EIB students.
探讨运动诱发支气管收缩与特应性之间的相关性。
通过自由跑步哮喘筛查试验定义运动诱发支气管收缩（EIB）。通过血清总IgE水平和皮肤过敏原试验定义特应性。通过支气管激发试验测定气道高反应性。对于配对研究，所有EIB学生和部分非EIB学生接受血清总IgE测量、皮肤过敏原试验和支气管激发试验。所有数据通过相关性分析计算，以研究EIB与特应性之间的相关性。
共有773名学生参加了自由跑步筛查试验，89名学生（11.5%）被诊断为患有EIB。89名EIB学生中有16名血清总IgE水平超过正常范围，而70名非EIB学生中有10名超过正常范围。统计学分析（χ²检验）不支持特应性与EIB之间的相关性。50名EIB学生接受了支气管激发试验，但只有1名表现出气道高反应性。
特应性与EIB之间无相关性，且大多数EIB学生不存在气道高反应性。
