Department of Pediatrics, Medisch Spectrum Twente, VKC poli 17, Haaksbergerstraat 55, Enschede 7513 ER, The Netherlands.
Immunol Allergy Clin North Am. 2013 Aug;33(3):381-94, viii-ix. doi: 10.1016/j.iac.2013.02.007. Epub 2013 Mar 27.
Recent research shows important differences in exercise-induced bronchoconstriction (EIB) between children and adults, suggesting a different pathophysiology of EIB in children. Although exercise can trigger classic symptoms of asthma, in children symptoms can be subtle and nonspecific; parents, children, and clinicians often do not recognize EIB. With an age-adjusted protocol, an exercise challenge test can be performed in children as young as 3 years of age. However, an alternative challenge test is sometimes necessary to assess potential for EIB in children. This review summarizes age-related features of EIB and recommendations for assessing EIB in young children and adolescents.
最近的研究表明，儿童和成人在运动诱发的支气管收缩（EIB）方面存在重要差异，这表明儿童 EIB 的病理生理学机制不同。尽管运动可以引发哮喘的典型症状，但在儿童中，症状可能很轻微且不具特异性；父母、儿童和临床医生通常无法识别 EIB。采用年龄调整方案，3 岁及以上的儿童即可进行运动挑战测试。然而，有时需要替代的挑战测试来评估儿童的 EIB 潜力。本综述总结了 EIB 的与年龄相关的特征，并提出了评估幼儿和青少年 EIB 的建议。
