[Evaluation of large doses of vitamin E in the treatment of anemia in patients with chronic renal failure].

The studied group comprised 10 patients with chronic renal failure on a programme of extracorporeal haemodialyses continued since 4 to 52 months, in whom the haematocrit value obtained during monthly laboratory investigations was below 21%, and who required at least one blood transfusion in three months. Before the study, after 3 months of treatment with vitamin E 600 mg in 24 hours, and 3 months after the completion of this treatment the following parameters were analysed: haemoglobin level, erythrocyte count, volume of blood transfused in various periods of the treatment. A slight rise of haematocrit value, haemoglobin level and erythrocyte count was observed after vitamin E treatment, but this rise was not significant statistically. No effect of vitamin E was noted on the osmotic resistance of the erythrocytes and the amount of blood transfused in the observed time periods. No side effects of vitamin E were noted.