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[主动脉冠状动脉搭桥术不同阶段缺血性心脏病患者心肌微循环床的超微结构]

[Ultrastructure of myocardial microcirculatory bed in patients with ischemic heart disease at various stages of aortocoronary bypass].

作者信息

Sheremet'eva G F, Ivanova A G, Martynov A A, Belov Iu V

出版信息

Vestn Akad Med Nauk SSSR. 1990(10):10-3.

PMID:2278174
Abstract

Changes in the ultrastructure of microcirculatory vasculature were studied on 136 puncture biopsy samples of the left ventricular myocardium taken from 56 ischemic heart disease patients before aortic compression, at terminal cardioplegia, and after coronary flow reconstruction. It was found, that changes in the endothelial cells gradually grow during cardioplegia, becoming statistically significant in the reconstructive post-cardioplegia period lasting over 60 min, which affects the capillary permeability, status of homeostasis and metabolism, and contractility of cardiomyocytes in the postoperative period.

摘要

对56例缺血性心脏病患者在主动脉阻断前、心脏停搏末期以及冠状动脉血流重建后取自左心室心肌的136份穿刺活检样本进行研究,以观察微循环血管超微结构的变化。研究发现,心脏停搏期间内皮细胞的变化逐渐加剧,在心脏停搏后持续超过60分钟的重建期内具有统计学意义,这会影响术后毛细血管通透性、内环境稳态和代谢状态以及心肌细胞的收缩性。

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