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[心脏瓣膜发育异常作为心脏手术中瓣膜关闭不全的原因(临床形态学相关性)]

[Heart valve dysplasia as a cause of valvular insufficiency in cardiac surgery (clinico-morphological correlations)].

作者信息

Alekseeva L A, Dzemeshkevich S L, Sheremet'eva G F, Morozova M M, Fishkova Z P, Kulagina T I

出版信息

Vestn Akad Med Nauk SSSR. 1990(10):13-7.

PMID:2278175
Abstract

Dysplasias underlying the mitral and aortic valve diseases in the presence of valvular incompetence were identified in 110 patients with a history of valve replacement. The morphological and electron microscopy evidence together with combinations of valvular changes with Marfan's syndrome and Erdheim's disease, and in some cases with minimal changes in the aorta and peripheral vessels, which followed the type of idiopathic cystic medionecrosis without aneurysm formation support the idea of the dysplastic etiology of the detected abnormalities. The occurrence of a heart disease in the presence of dysplasia is determined by the extent of a valvular process and attending complications, such as chordal rupture or septic endocarditis.

摘要

在110例有瓣膜置换史的患者中,发现了存在瓣膜关闭不全情况下二尖瓣和主动脉瓣疾病的发育异常。形态学和电子显微镜证据,以及瓣膜变化与马方综合征和厄尔德海姆病的组合,在某些情况下主动脉和外周血管变化极小,符合无动脉瘤形成的特发性囊性中膜坏死类型,支持了所检测到的异常具有发育异常病因的观点。发育异常情况下心脏病的发生取决于瓣膜病变的程度及伴随的并发症,如腱索断裂或感染性心内膜炎。

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