School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China.
Chemistry. 2012 Aug 20;18(34):10497-500. doi: 10.1002/chem.201200949. Epub 2012 Jul 10.
In the zone: Pd-catalyzed oxidative cross-coupling of N-tosylhydrazones with allylic alcohols leads to CC bond formation. A palladium-carbene migratory insertion is proposed to play the key role in this transformation. The reaction proceeds with readily available starting materials to afford substituted alkenes in a highly stereoselective manner.
Pd 催化的 N-对甲苯磺酰腙与烯丙醇的氧化交叉偶联导致 CC 键形成。提出钯-卡宾迁移插入在这种转化中起关键作用。该反应以易得的起始原料进行，以高立体选择性地提供取代的烯烃。
