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呼吸急促感知迟钝对老年人医疗服务利用、医疗支出及死亡率的影响。

Impact of blunted perception of dyspnea on medical care use and expenditure, and mortality in elderly people.

作者信息

Ebihara Satoru, Niu Kaijun, Ebihara Takae, Kuriyama Shinichi, Hozawa Atsushi, Ohmori-Matsuda Kaori, Nakaya Naoki, Nagatomi Ryoichi, Arai Hiroyuki, Kohzuki Masahiro, Tsuji Ichiro

机构信息

Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine Sendai, Japan.

出版信息

Front Physiol. 2012 Jul 4;3:238. doi: 10.3389/fphys.2012.00238. eCollection 2012.

Abstract

Dyspnea is an alarming symptom responsible for millions of patient visits each year. Poor perception of dyspnea might be reasonably attributed to an inappropriately low level of fear and inadequate earlier medical treatment for both patients and physicians, resulting in subsequent intensive care. This study was conducted to evaluate medical care use and cost, and mortality according to the perception of dyspnea in community-dwelling elderly people. We analyzed baseline data from a community-based Comprehensive Geriatric Assessment in 2002. The perception of dyspnea in 479 Japanese community-dwelling elderly people with normal lung function was measured in August 2002. The sensation of dyspnea during breathing with a linear inspiratory resistance of 10, 20, and 30 cmH(2)O/L/s was rated using the Borg scale. According to the perception of dyspnea, we divided the elderly into tertiles and compared all hospitalizations, out-patient visits, costs, and death through computerized linkage with National Health Insurance beneficiaries claims history files between August 2002 and March 2008. In-patient hospitalization days and medical care costs significantly increased with the blunted perception of dyspnea, resulting in an increase in total medical-costs with blunted perception of dyspnea. With low perception group as reference, the hazard ratios of all-cause mortality were 0.65 (95% CI 0.23-1.89) for intermediate perception group and 0.31 (0.10-0.97) for high perception group, indicating the mortality rate also significantly increased with the blunted perception of dyspnea after multivariates adjustment (p = 0.04). The blunted perception of dyspnea is related to hospitalization, large medical costs, and all-cause mortality in community-dwelling elderly people. These findings provide a rational for preventing serious illness with careful monitoring of objective conditions in the elderly.

摘要

呼吸困难是一种令人担忧的症状,每年导致数百万患者就诊。对呼吸困难的感知不佳可能合理地归因于患者和医生的恐惧水平过低以及早期医疗治疗不足,从而导致随后的重症监护。本研究旨在评估社区居住老年人对呼吸困难的感知与医疗使用、成本及死亡率之间的关系。我们分析了2002年一项基于社区的综合老年评估的基线数据。2002年8月,对479名肺功能正常的日本社区居住老年人的呼吸困难感知进行了测量。使用Borg量表对吸气阻力为10、20和30 cmH₂O/L/s时呼吸过程中的呼吸困难感觉进行评分。根据对呼吸困难的感知,我们将老年人分为三分位数,并通过与2002年8月至2008年3月期间国民健康保险受益人的索赔历史文件进行计算机链接,比较了所有住院、门诊就诊、费用和死亡情况。随着对呼吸困难感知的减弱,住院天数和医疗费用显著增加,导致呼吸困难感知减弱的总医疗费用增加。以低感知组为参照,中等感知组的全因死亡率风险比为0.65(95%可信区间0.23 - 1.89),高感知组为0.31(0.10 - 0.97),表明多变量调整后,随着呼吸困难感知的减弱,死亡率也显著增加(p = 0.04)。社区居住老年人对呼吸困难的感知减弱与住院、高额医疗费用和全因死亡率相关。这些发现为通过仔细监测老年人的客观状况来预防严重疾病提供了依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d730/3389490/5a3f3a8a8a2b/fphys-03-00238-g001.jpg

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