Kim Daejin, Kim Junhyung, Yeo Hyeonjung, Kwon Hyukjun, Son Daegu, Han Kihwan
Department of Plastic and Reconstructive Surgery, Keimyung University School of Medicine, Daegu, Korea.
Arch Plast Surg. 2012 Mar;39(2):143-9. doi: 10.5999/aps.2012.39.2.143. Epub 2012 Mar 14.
Axillary osmidrosis is characterized by an unpleasant odor, profuse sweating, and in some instances, staining of clothes that may socially and psychologically impair affected individuals. Various types of surgical procedures have been developed for the treatment of axillary osmidrosis. This study was undertaken to evaluate the effectiveness of subcutaneous pulsed neodymium: yttrium-aluminum-garnet (Nd-YAG) laser treatment for the treatment of axillary osmidrosis.
Twenty-nine patients with axillary osmidrosis were included in this study. Patients were categorized according to the results of an axillary malodor grading system, and a subcutaneous pulsed Nd-YAG laser was applied to all patients. The treatment area for the appropriate distribution of laser energy was determined using the iodine starch test (Minor's test) against a grid pattern composed of 2×2 cm squares. The endpoint of exposure was 300 to 500 J for each grid, depending on the preoperative evaluation results. The results were evaluated by measurement of axillary malodor both pre- and postoperatively using the grading system and iodine starch test.
The average follow-up period was 12.8 months. Nineteen patients had a fair-to-good result and ten patients had poor results. The postoperative Minor's test demonstrated that there were remarkable improvements for patients with mild to moderate symptoms. Complications including superficial second degree burns (n=3) were treated in a conservative manner. A deep second degree burn (n=1) was treated by a surgical procedure.
Subcutaneous pulsed Nd-YAG laser has many advantages and is an effective noninvasive treatment for mild to moderate axillary osmidrosis.
腋部臭汗症的特征为难闻气味、多汗,在某些情况下还会导致衣物染色,这可能会对患者的社交和心理造成损害。已经开发出多种外科手术方法来治疗腋部臭汗症。本研究旨在评估皮下脉冲钕:钇铝石榴石(Nd-YAG)激光治疗腋部臭汗症的有效性。
本研究纳入了29例腋部臭汗症患者。根据腋部异味分级系统的结果对患者进行分类,并对所有患者应用皮下脉冲Nd-YAG激光。使用碘淀粉试验(Minor试验)针对由2×2平方厘米正方形组成的网格图案来确定激光能量适当分布的治疗区域。根据术前评估结果,每个网格的暴露终点为300至500焦耳。通过使用分级系统和碘淀粉试验在术前和术后测量腋部异味来评估结果。
平均随访期为12.8个月。19例患者效果良好至中等,10例患者效果不佳。术后Minor试验表明,轻度至中度症状的患者有显著改善。包括浅表二度烧伤(n = 3)在内的并发症采用保守治疗。1例深部二度烧伤通过手术治疗。
皮下脉冲Nd-YAG激光具有许多优点,是治疗轻度至中度腋部臭汗症的一种有效的非侵入性方法。