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麻风病患者认知障碍的初步研究。

A preliminary study of locognosia in people affected by leprosy.

作者信息

Ebenezer M, Nail K, Pradeepa N

机构信息

Head Branch of Surgery, Schieffelin Institute of Health-Research and Leprosy Centre, Karigiri-632 106, Vellore, India.

出版信息

Indian J Lepr. 2011 Oct-Dec;83(4):209-13.

Abstract

Locognosia is the ability to localize a sensory stimulus on the body's surface and can be tested by graded filaments (Semmes-Weinstein monofilaments). This point localization of sensation (locognosia) wastested by SW filaments over four quadrants of the pulp of the fingers in ulnar/median and ulnar paralysis in 38 new patients affected by leprosy. The results were compared with standard testing of sensation at selected sites by Semmes Weinstein monofilament. Both pulp quadrant testing and standard site testing were done in leprosy patients and also in a group of controls. Sensation was tested in 73 hands in leprosy patients and 34 hands in controls. Results indicate a positive correlation between locognosia and standard SW filament testing. When locognosia and standard SW filament tests were compared, there was significant difference between the two tests to pick up abnormal sensation in leprosy patients both over the entire hand and over individual fingers. This preliminary study suggests that locognosia may be a useful tool to diagnose sensory impairment in leprosy. Further studies are required to corroborate this.

摘要

定位觉是指将体表感觉刺激定位的能力,可通过分级细丝(Semmes-Weinstein单丝)进行测试。在38例新诊断的麻风病患者中,采用Semmes-Weinstein细丝对尺神经/正中神经麻痹及尺神经麻痹患者手指 pulp的四个象限进行感觉点定位(定位觉)测试。将结果与通过Semmes Weinstein单丝在选定部位进行的标准感觉测试进行比较。在麻风病患者和一组对照中均进行了pulp象限测试和标准部位测试。对73例麻风病患者的手和34例对照的手进行了感觉测试。结果表明定位觉与标准Semmes-Weinstein细丝测试之间存在正相关。当比较定位觉和标准Semmes-Weinstein细丝测试时,在整个手部和各个手指上检测麻风病患者异常感觉的两种测试之间存在显著差异。这项初步研究表明,定位觉可能是诊断麻风病感觉障碍的有用工具。需要进一步的研究来证实这一点。

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