Department of Pathology, Northwestern University McGaw Medical Center, Chicago, Illinois 60611, USA.
Neuropathology. 2013 Apr;33(2):192-8. doi: 10.1111/j.1440-1789.2012.01337.x. Epub 2012 Jul 12.
Chordoid meningioma is an uncommon variant of meningioma, and is very rarely found in the pineal region. We report a case of pineal region chordoid meningioma occurring in a young woman complicated by repetitive hemorrhages in the setting of pregnancy. A 23-year-old woman, 28 weeks pregnant, was transferred to our hospital for further management of a multi-septated, hemorrhagic pineal region mass and hydrocephalus. MRI revealed a heterogeneous T2-hyperintense lesion measuring 1.7 × 1.7 cm in the pineal gland. Resection of the tumor through an occipital transtentorial approach was performed. Histopathologic examination of the lesion confirmed the diagnosis of chordoid meningioma demonstrating cords and clusters of eosinophilic cells with rare cytoplasmic vacuolation arranged in a mucinous stroma. Additionally, there was abundant lymphoplasmacytic infiltration within the tumor. The details of this case are presented with a review of the literature.
脊索样脑膜瘤是脑膜瘤的一种罕见变异型，极少见发生于松果体区。我们报告了 1 例妊娠合并复发性出血的年轻女性松果体区脊索样脑膜瘤病例。1 例 23 岁、妊娠 28 周的女性因多房性、出血性松果体区肿块和脑积水被转入我院进一步治疗。MRI 显示松果体区 1.7×1.7cm 的混杂 T2 高信号病变。通过枕骨经天幕入路进行肿瘤切除术。病变的组织病理学检查证实为脊索样脑膜瘤，表现为条索状和簇状嗜酸性细胞，罕见细胞质空泡，排列在黏液样基质中。此外，肿瘤内有丰富的淋巴浆细胞浸润。本文报道了该病例的详细情况，并复习了相关文献。
