Department of Clinical Sciences in Malmö, Cardiovascular Epidemiology, Lund University, Sweden.
Scand J Public Health. 2012 Jun;40(4):340-7. doi: 10.1177/1403494812449078.
In western countries out-of-hospital ischaemic heart disease (IHD) deaths account for approximately 50-70% of all IHD deaths. The objective was to examine the trends in out-of-hospital IHD deaths in the Region of Skåne in southern Sweden, in different sex- and age-groups.
All 14,347 persons (range 24-110 years) in Skåne who died out-of-hospital between 1992 and 2003 from IHD (I410-I414; I20-I25) as the underlying cause of death. Subjects with previous admission for IHD since 1970 were excluded. Data were retrieved from the Swedish National Cause of Death and Patient Register. Age-standardized IHD mortality rates and trends were calculated using Poisson regression analysis.
Age-standardized annual out-of-hospital IHD mortality rates from 1992-2003 decreased in men from 177±13 to 103±9/100,000 inhabitants (-4.7%; p<0.001) and in women from 142±11 to 96±9/100,000 (-2.7%; p<0.001). In men, the annual change in age-standardized IHD mortality rates were -5.3 % (p<0.001), -4.0 % (p<0.001) and -4.7 % (p<0.001), respectively, in the age groups 20-64 years, 65-74 years and ≥75 years. Corresponding figures in women were -4.4 % (p<0.001), -2.4 % (p=0.003) and -2.5 % (p<0.001). The proportion of IHD deaths occurring out-of-hospital was in these age groups 50%, 40% and 35% respectively.
In Skåne, out-of-hospital mortality in IHD deaths decreased significantly between 1992 and 2003. The decrease is more pronounced in men than women, and at the end of the study period in 2003, rates were almost equal. The proportion of IHD deaths occurring outside hospital was higher in younger people than in older people.
在西方国家,院外缺血性心脏病(IHD)死亡约占所有 IHD 死亡的 50-70%。本研究旨在探讨瑞典斯科讷地区不同性别和年龄组的院外 IHD 死亡趋势。
所有 1992 年至 2003 年期间在斯科讷地区院外因 IHD(I410-I414;I20-I25)作为根本死因死亡的 14347 名(年龄 24-110 岁)患者。排除 1970 年以来因 IHD 入院的患者。数据来自瑞典国家死因和患者登记处。使用泊松回归分析计算年龄标准化 IHD 死亡率和趋势。
1992-2003 年,男性院外 IHD 死亡率从 177±13 降至 103±9/100000 居民(-4.7%;p<0.001),女性从 142±11 降至 96±9/100000(-2.7%;p<0.001)。在男性中,年龄标准化 IHD 死亡率的年变化率分别为-5.3%(p<0.001)、-4.0%(p<0.001)和-4.7%(p<0.001),年龄组分别为 20-64 岁、65-74 岁和≥75 岁。女性相应数字为-4.4%(p<0.001)、-2.4%(p=0.003)和-2.5%(p<0.001)。这些年龄组的 IHD 死亡中,院外死亡的比例分别为 50%、40%和 35%。
在斯科讷,1992 年至 2003 年期间,院外 IHD 死亡人数显著下降。男性的降幅大于女性,到研究期末 2003 年,死亡率几乎相等。院外发生的 IHD 死亡比例在年轻人中高于老年人。