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Reversible cerebral vasoconstriction syndromes: analysis of 139 cases.可逆性脑血管收缩综合征:139例分析
Arch Neurol. 2011 Aug;68(8):1005-12. doi: 10.1001/archneurol.2011.68. Epub 2011 Apr 11.
2
Magnetic resonance angiography in reversible cerebral vasoconstriction syndromes.磁共振血管造影在可逆性脑血管收缩综合征中的应用。
Ann Neurol. 2010 May;67(5):648-56. doi: 10.1002/ana.21951.
3
Reversible cerebral vasoconstriction syndrome presenting with haemorrhage.以出血为表现的可逆性脑血管收缩综合征
J Neurol Sci. 2009 Jan 15;276(1-2):189-92. doi: 10.1016/j.jns.2008.08.034. Epub 2008 Oct 2.
4
Transcranial color doppler study for reversible cerebral vasoconstriction syndromes.经颅彩色多普勒对可逆性脑血管收缩综合征的研究
Ann Neurol. 2008 Jun;63(6):751-7. doi: 10.1002/ana.21384.
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The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome. A prospective series of 67 patients.可逆性脑血管收缩综合征的临床及影像学表现。一项对67例患者的前瞻性研究。
Brain. 2007 Dec;130(Pt 12):3091-101. doi: 10.1093/brain/awm256. Epub 2007 Nov 19.
6
Narrative review: reversible cerebral vasoconstriction syndromes.叙述性综述:可逆性脑血管收缩综合征
Ann Intern Med. 2007 Jan 2;146(1):34-44. doi: 10.7326/0003-4819-146-1-200701020-00007.
7
Recurrent primary thunderclap headache and benign CNS angiopathy: spectra of the same disorder?复发性原发性霹雳样头痛与良性中枢神经系统血管病:同一疾病的不同表现?
Neurology. 2006 Dec 26;67(12):2164-9. doi: 10.1212/01.wnl.0000249115.63436.6d.
8
Benign cerebral angiopathy; postpartum cerebral angiopathy: characteristics and treatment.
Curr Treat Options Cardiovasc Med. 2006 May;8(3):201-12. doi: 10.1007/s11936-006-0013-y.
9
Serotonin-induced inhibition of KV current: a supporting role in pulmonary vasoconstriction?血清素诱导的钾离子电流抑制:在肺血管收缩中起辅助作用?
Circ Res. 2006 Apr 14;98(7):860-2. doi: 10.1161/01.RES.0000219683.65556.74.
10
Triptan-induced contractile (5-HT1B receptor) responses in human cerebral and coronary arteries: relationship to clinical effect.曲坦类药物诱发的人脑血管和冠状动脉收缩(5-HT1B受体)反应:与临床疗效的关系。
Clin Sci (Lond). 2005 Sep;109(3):335-42. doi: 10.1042/CS20050016.

一种可逆性脑血管收缩综合征。

A reversible cerebral vasoconstriction syndrome.

作者信息

Ba Fang, Giuliani Fabrizio, Camicioli Richard, Saqqur Maher

机构信息

Division of Neurology, University of Alberta, Edmonton, Canada.

出版信息

BMJ Case Rep. 2012 Jul 11;2012:bcr0920114841. doi: 10.1136/bcr.09.2011.4841.

DOI:10.1136/bcr.09.2011.4841
PMID:22787186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3417010/
Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is typically presented with severe headaches where, vascular imaging demonstrates multiple intracranial arterial narrowing. Variable triggers are related to RCVS, such as serotonin agents and bromocriptine. Thus, a detailed medication history is important. Subarachnoid haemorrhage (SAH) is not uncommon in RCVS. Repeat vascular imaging at 2-3 months with complete reversal of the narrowed vessels confirms the diagnosis of RCVS. The authors present a case where use of triptan along with multiple psychotropic medications, was associated with RVCS. Neuroimaging demonstrated focal SAH and diffuse beaded appearance involving the intracranial vasculature. The patient improved clinically with oral nimodipine treatment. Repeat angiography and a follow-up transcranial Doppler showed complete resolution of vasoconstriction. In the setting of acute severe headache, with any 'red flags', it is important to evaluate the medication use and other precipitating risks for RVCS. Vascular imaging is the key for diagnosis.

摘要

可逆性脑血管收缩综合征(RCVS)通常表现为严重头痛,血管成像显示多条颅内动脉狭窄。RCVS有多种诱发因素,如血清素类药物和溴隐亭。因此,详细的用药史很重要。蛛网膜下腔出血(SAH)在RCVS中并不少见。在2 - 3个月时重复血管成像,狭窄血管完全逆转可确诊RCVS。作者报告了一例使用曲坦类药物及多种精神药物与RCVS相关的病例。神经影像学显示局灶性SAH和颅内血管弥漫性串珠样表现。患者口服尼莫地平治疗后临床症状改善。重复血管造影和随访经颅多普勒显示血管收缩完全缓解。在急性严重头痛伴有任何“警示信号”的情况下,评估药物使用情况和其他RCVS的诱发风险很重要。血管成像是诊断的关键。