中国瑶族人群中HLAⅢ类基因和GLO1基因的遗传多态性

Genetic polymorphisms of HLA class III and GLO1 in Chinese Yao nationality.

作者信息

Wang C, Tian Y W, Wu X W, Zhao X Z

机构信息

Department of Patophysiology, Tongji Medical University, Wuhan, P.R. of China.

出版信息

Gene Geogr. 1990 Apr;4(1):29-34.

PMID:2278900

Abstract

Yao is one of the minority nationalities located mainly in the South of China (Guang Xi province). The purpose of this study was to examine HLA class III and GLO1 in Yao nationality to identify the difference between Yao and Han. Han is the major nationality in China. Yao has the lowest C2C frequency (0.9336) in the world. Before this study the lowest C2C frequency known was that of the Japanese (0.9386). Gene frequencies in Yao are the following: C2C = 0.9336, C2B = 0.0664; BFS = 0.9071, BFF = 0.0929; C4A4 = 0.0253, C4A3 = 0.6061, C4A2 = 0.2121, C4A1 = 0.0152, C4AQ0 = 0.1414; C4B3 = 0.0051, C4B2 = 0.0657, C4B1 = 0.7071, C4B92 = 0.0455, C4B95 = 0.0253, C4B96 = 0.0253, C4B12 = 0.0051, C4BQ0 = 0.1212; GLO11 = 0.1161, GLO1*2 = 0.8839. We have compared these data with those reported for Han.

摘要

瑶族是主要分布在中国南部（广西省）的少数民族之一。本研究的目的是检测瑶族的HLAⅢ类基因和GLO1基因，以确定瑶族与汉族之间的差异。汉族是中国的主要民族。瑶族拥有世界上最低的C2C频率（0.9336）。在本研究之前，已知最低的C2C频率是日本人的（0.9386）。瑶族的基因频率如下：C2C = 0.9336，C2B = 0.0664；BFS = 0.9071，BFF = 0.0929；C4A4 = 0.0253，C4A3 = 0.6061，C4A2 = 0.2121，C4A1 = 0.0152，C4AQ0 = 0.1414；C4B3 = 0.0051，C4B2 = 0.0657，C4B1 = 0.7071，C4B92 = 0.0455，C4B95 = 0.0253，C4B96 = 0.0253，C4B12 = 0.0051，C4BQ0 = 0.1212；GLO11 = 0.1161，GLO1*2 = 0.8839。我们已将这些数据与报道的汉族数据进行了比较。