The Haven, Effie Road, London SW6 1TB, UK.
Complement Ther Clin Pract. 2012 Aug;18(3):182-9. doi: 10.1016/j.ctcp.2012.03.002. Epub 2012 May 3.
A pilot study was conducted to assess recruitment and effectiveness of an integrated support programme in women with breast cancer. Twelve participants were randomised to receive medical care with or without the support programme. Psychosocial questionnaires and immune/hormonal assays were completed at baseline, three and six months. Recruitment was problematic. In the intervention group, mental fatigue was significantly improved (p = 0.016) compared to controls; increased NK cell activity suggested an improvement in immune function. Total stress (p = 0.009), anxiety (p = 0.032) and endocrine-specific (p = 0.032) symptoms were significantly improved in the controls. A large-scale randomisation trial appears warranted, dependent upon effective recruitment.
一项初步研究旨在评估乳腺癌女性综合支持计划的招募情况和效果。12 名参与者被随机分配接受医疗护理或同时接受支持计划。在基线、3 个月和 6 个月时完成心理社会问卷和免疫/激素检测。招募存在问题。在干预组中，与对照组相比，精神疲劳显著改善（p = 0.016）；NK 细胞活性增加表明免疫功能改善。对照组的总应激（p = 0.009）、焦虑（p = 0.032）和内分泌特异性（p = 0.032）症状显著改善。一项大规模随机试验似乎是合理的，取决于有效的招募。
