Yasuda Seiichi, Komatsubara Takashi, Inamoto Susumu, Lee Jeong, Teramura Yasufumi, Hashida Shuhei, Akamatsu Shin
Dept. of Surgery, Hikone Municipal Hospital, Japan.
Gan To Kagaku Ryoho. 2012 Jul;39(7):1135-8.
A 54-year-old man underwent distal gastrectomy for early gastric cancer in September 2002. CT performed 6 months after the operation revealed liver metastases, and they were resected. Hepatic arterial infusion therapy of 5-FU was performed; however, multiple liver metastases appeared in October 2003. We added arterial infusion of CDDP to 5-FU, but liver metastases increased. We then applied a combination chemotherapy of S-1 and paclitaxel from February 2004. Subsequently, stable disease continued, and after 67 courses of S-1 plus paclitaxel, we changed the administration to S-1 alone from August 2009. After that, liver metastases did not increase, so we discontinued chemotherapy on August 2010, followed by observation. Progression of liver metastases has not been to date.
