使用支架催化高效去对称甘油。
The efficient desymmetrization of glycerol using scaffolding catalysis.
机构信息
Boston College, Merkert Chemistry Center, 2609 Beacon, St. Chestnut Hill, MA 02467-3860, USA.
出版信息
Chem Commun (Camb). 2013 May 14;49(39):4370-2. doi: 10.1039/c2cc33633b.
Abstract
Glycerol is an ideal building block for the synthesis of complex molecules, because it is inexpensive and highly functionalized. We report the desymmetrization of glycerol through silyl transfer, using a chiral organic catalyst in high yield and enantioselectivity.
摘要
甘油是合成复杂分子的理想结构单元，因为它价格低廉且高度官能化。我们报告了通过硅转移对甘油进行去对称化，使用手性有机催化剂可高产率和高对映选择性地实现。
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