Iseki Chifumi, Takahashi Yoshimi, Wada Manabu, Arawaka Shigeki, Kawanami Toru, Kato Takeo
Department of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology, Faculty of Medicine, Yamagata University, Japan.
Intern Med. 2012;51(13):1751-3. doi: 10.2169/internalmedicine.51.7254. Epub 2012 Jul 1.
We report on an 80-year-old woman who had shunt-responsive idiopathic normal pressure hydrocephalus (iNPH). Her brain MRI showed an initial change in the subarachnoid space (a disproportional narrowing of the subarachnoid space at the cerebral high convexities) at the age of 70 years, followed by enlargement of the ventricles (Evans index: 0.31) at the age of 78. The observation suggests that changes in the subarachnoid space may precede ventricular enlargement in iNPH.
我们报告了一位80岁患有分流反应性特发性正常压力脑积水(iNPH)的女性。她的脑部MRI显示,70岁时蛛网膜下腔出现初始变化(脑高凸处蛛网膜下腔不成比例地变窄),随后在78岁时脑室扩大(埃文斯指数:0.31)。该观察结果表明,在iNPH中蛛网膜下腔的变化可能先于脑室扩大。