Galat A
Department of Chemistry, Harvard University, Cambridge, MA 02138.
J Mol Graph. 1990 Sep;8(3):173-8. doi: 10.1016/0263-7855(90)80060-s.
A graphical procedure for analysis of helical parameters in dynamic structure of DNA is described. The performance of the procedure is illustrated by analysis of a 20 ps dynamics simulation of the non-self-complementary ninemer, 5'CAAACAGGA:5'TCCTGTTTG, which is a part of DNA from lacI gene. The dynamics trajectory of the duplex shows sequence-dependent fluctuations of helical parameters.
描述了一种用于分析DNA动态结构中螺旋参数的图形化方法。通过对非自互补九聚体5'CAAACAGGA:5'TCCTGTTTG(lacI基因DNA的一部分)的20皮秒动态模拟分析,展示了该方法的性能。双链体的动力学轨迹显示了螺旋参数的序列依赖性波动。