Department of Radiology, Kinki University, Faculty of Medicine, Osaka-Sayama, Japan.
Magn Reson Med Sci. 2012;11(2):75-81. doi: 10.2463/mrms.11.75.
Detection, characterization, staging, and treatment monitoring are major roles of diagnostic imaging of liver cancers. Developments in multidetector-row computed tomography (MDCT) technology have increased the spatial and temporal resolution of CT to allow more precise evaluation of the hemodynamics of liver tumors and improve the diagnostic accuracy of dynamic MDCT. The high spatial and temporal resolutions of dynamic MDCT enable us to reconstruct 3-dimensional (3D) images that are very useful for pretreatment evaluation. Dynamic MR imaging with fast 3D T(1)-weighted gradient echo imaging sequence using nonspecific contrast medium can be highly sensitive for detecting hypervascular HCC. However, the use of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA), a contrast medium specific to hepatic tissue, offers greater diagnostic ability and, so, has become essential to liver imaging. MR imaging with Gd-EOB-DTPA may replace CT during hepatic arteriography and CT during arterioportography.
检测、特征描述、分期和治疗监测是肝癌诊断影像学的主要作用。多排探测器 CT（MDCT）技术的发展提高了 CT 的空间和时间分辨率，使我们能够更精确地评估肝肿瘤的血液动力学，并提高动态 MDCT 的诊断准确性。动态 MDCT 的高空间和时间分辨率使我们能够重建非常有助于预处理评估的三维（3D）图像。使用非特异性对比剂的快速 3D T1 加权梯度回波成像序列的动态 MR 成像对检测富血供 HCC 具有非常高的敏感性。然而，使用特异性肝脏组织对比剂钆塞酸二钠（Gd-EOB-DTPA）可提供更大的诊断能力，因此对肝脏成像至关重要。Gd-EOB-DTPA 的 MR 成像可能会在肝动脉造影期间取代 CT，也可能会在动脉造影期间取代 CT。
