Murata Atsuhiko, Okamoto Kohji
Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Japan.
Nihon Shokakibyo Gakkai Zasshi. 2012 Jul;109(7):1197-203.
We collected data from 2070 patients who had undergone cholecystectomy for acute cholecystitis, investigating the circumstance of preoperative antimicrobial therapy. The duration of preoperative antimicrobial therapy was significantly longer in delayed cholecystectomy than early cholecystectomy (p<0.001). The number of types of antimicrobial drugs was also significantly greater in delayed cholecystectomy patients. The length of preoperative hospital stay in accordance with the number of antimicrobial drugs used in delayed cholecystectomy (p<0.001). This study suggests the importance of early cholecystectomy and the appropriate use of preoperative antimicrobial drugs for acute cholecystitis.