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评估无创每搏量变异监测在嗜铬细胞瘤患者腹腔镜肾上腺切除术期间调整液体补充中的作用。

Examination of the usefulness of non-invasive stroke volume variation monitoring for adjusting fluid supplementation during laparoscopic adrenalectomy in patients with pheochromocytoma.

作者信息

Isosu Tsuyoshi, Obara Shinju, Ohashi Satoshi, Hosono Atsuyuki, Nakano Yuko, Imaizumi Tsuyoshi, Mogami Midori, Iida Hiroshi, Murakawa Masahiro

机构信息

Department of Anesthesiology, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima, Japan.

出版信息

Fukushima J Med Sci. 2012;58(1):78-81. doi: 10.5387/fms.58.78.

Abstract

PURPOSE OF THE STUDY

The measurement of stroke volume variation (SVV) using the FloTrac™ system (Edwards Lifescience, USA) is useful to estimate cardiac preload. We evaluated the benefits of SVV monitoring for adjusting fluid supplementation during laparoscopic adrenalectomy under anesthesia in patients with pheochromocytoma.

SUBJECTS AND METHODS

Among 10 patients who underwent laparoscopic adrenalectomy for pheochromocytoma in our institution from June 2004 to December 2009, SVV was not monitored in 5 patients (group I) and in the other 5 patients (group II), SVV monitoring was performed. Subject age, height and body weight, total volume of fluid supplemented, blood loss, urine output and net fluid in-out balance during the procedure were retrospectively assessed. In those with SVV monitoring, infusion volume was adjusted for SVV less than 13%.

RESULTS

There were significant differences in the patient age and body weight between the two groups (group I: 64.2 years old and 55.1 kg; group II: 43.6 years old and 71.7 kg). Both total infusion volume and urine output were significantly higher in group I compared with group II (5,610 vs. 2,400 ml and 1,125 vs. 750 ml, respectively). Total blood loss was similar between the two groups. Values of the net fluid balance divided by the body weight and total anesthesia period (hr) were significantly lower in group II compared with group I (I; +13.2 in group I and +6.2 in group II, ml/kg/hr).

CONCLUSIONS

These data suggest that SVV monitoring is helpful to estimate the optimal volume for fluid supplementation and could prevent excessive fluid infusion during surgical procedures.

摘要

研究目的

使用FloTrac™系统(美国爱德华生命科学公司)测量每搏量变异度(SVV)有助于评估心脏前负荷。我们评估了在嗜铬细胞瘤患者麻醉下行腹腔镜肾上腺切除术期间,监测SVV对调整液体补充的益处。

对象与方法

2004年6月至2009年12月在我院接受腹腔镜嗜铬细胞瘤肾上腺切除术的10例患者中,5例患者(I组)未监测SVV,另外5例患者(II组)进行了SVV监测。回顾性评估患者的年龄、身高、体重、术中补充液体总量、失血量、尿量及液体净出入量。对于监测SVV的患者,当SVV小于13%时调整输液量。

结果

两组患者的年龄和体重存在显著差异(I组:64.2岁,55.1kg;II组:43.6岁,71.7kg)。I组的总输液量和尿量均显著高于II组(分别为5610 vs. 2400ml和1125 vs. 750ml)。两组的总失血量相似。II组的液体净平衡值除以体重和总麻醉时间(小时)显著低于I组(I组为+13.2,II组为+6.2,ml/kg/hr)。

结论

这些数据表明,监测SVV有助于评估最佳液体补充量,并可防止手术过程中液体输注过多。

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